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KMID : 1161920200170020060
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Journal of Medicine and Life Science
2020 Volume.17 No. 2 p.60 ~ p.63
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Primary hyperaldosteronism with aldosterone producing adenoma and hyperplasia: 1 case
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Park Hye-Won
Lee Sang-Ah
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Abstract
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Primary hyperaldosteronism is being diagnosed increasingly often. As many as up to 20% of patients with hypertension have the characteristic laboratory increased aldosterone/plasma renin activity ratio. Primary hyperaldosteronism is due to aldosterone-producing adenoma, bilateral adrenal hyperplasia or rarely, adrenal carcinoma or genetic causes. The diagnostic test of hyperaldosteronism is saline loading test usually, captopril test, or other tests. If planned surgery, adrenal vein sampling was necessary for localization. Primary hyperaldosteronism has treated with the aldosterone antagonist spironolactone as the drug of choice. It is used to patients with aldosterone producing adenoma or hyperplasia, because of spironolactone well controlled hypertension in most of primary hyperaldosteronism patients. However, unilateral laparoscopic adrenalectomy is usual treatment for aldosterone producing adenoma or asymmetrical aldostererone production of patients with uncontrolled hypertension. We experienced primary hyperaldosteronism patients successfully treated with unilateral adrenalectomy, who has uncontrolled hypertension through treated with 5 antihypertensive medications and with both adrenal adenoma and adrenal hyperplasia.
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KEYWORD
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Aldosteronism, Adenoma, Hyperplasia
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